Chembl
NPM · @PIPEWORX/MCP-CHEMBL · 2 COMPONENTS
ChEMBL MCP — drug discovery database (EBI).
Available components
Last scanned (4 hours ago)
Scores higher than 72% of npm servers
Category Health and Science
How this component scores in each security and reliability category. Every signal is checked automatically from public evidence about the published package, including repeated runs of it in an isolated sandbox, and we only credit what we can confirm. How we score → Why this is hard to score →
Supply Chain Security100
- No malware found by supply-chain analysis.Pass
- No known CVEs affecting this package version or its production dependencies.Pass
- No install/post-install scripts declared.Pass
- No production dependencies, so there is no dependency health to assess. View diagnostics → Pass
Provenance & Transparency97
- Source repository is publicly reachable at the declared URL. View diagnostics → Pass
- Cryptographically verified build provenance (signed, bound to pipeworx-io/mcp-chembl). View diagnostics → Pass
- Clear OSI-approved license (MIT).Pass
- Actively maintained (last published 5 days ago).Pass
- Disclosure check failed: no security disclosure policy was found in the source repository. See how to fix → Fail
Schema Quality & AI Usability67
- AI-judged instruction clarity (good).Pass
- Context-footprint check failed: tool/resource definitions use about 982 tokens (~140/item across 7 items; 7 tools + 0 resources), over budget; trim descriptions and params. See how to fix → Fail
- Usage-examples check failed: none of the tools include examples. See how to fix → Fail
Stability & Change Management23
- Stability observed for 7 of 30 days with no destabilising changes; credit accrues until the full window elapses.Partial
Tool Coverage88
- 100% of tools have a non-trivial description (not blank, and not just the tool's name).Pass
- 65% of tool parameters carry a description.Partial
Tool Safety100
- No prompt-injection markers were found in the server instructions, tool names or descriptions we captured.Pass
- We read all 7 captured tool definition(s), and no name or description among them implies an irreversible operation.Pass
- An AI judge read all 8 captured unit(s) of tool text and found none that tries to manipulate the model reading it.Pass
Capabilities100
- Implements a supported MCP spec version (2025-11-25); the latest is 2026-07-28.Pass
Every change we have recorded for this component, newest first. Security-relevant changes are always shown. ▲ marks a change for the better, ▼ a change for the worse; unmarked changes are neutral.
- 5 Nov 26 +1
No change was recorded against any check on this day. Stability & Change Management went from 20 to 23. That category is still filling its 30-day observation window: 6 days of observed history at the previous scan, 7 at this one. The score rises as the window fills, whether or not the server changes.
- 3 Nov 26 +1
No change was recorded against any check on this day. Stability & Change Management went from 13 to 17. That category is still filling its 30-day observation window: 4 days of observed history at the previous scan, 5 at this one. The score rises as the window fills, whether or not the server changes.
- 1 Nov 26 +16
- Malware scan: unverified → pass ▲ security
- 31 Oct 26 −15
- Malware scan: pass → unverified ▼ security
- Package version: 0.2.0 → 0.2.1 functional
- 29 Oct 26 79
First indexed and scored.
Diagnostic detail from the automated scan of this channel: what the scanner observed at each step, so you can see exactly where a check passed or failed. It is informational only and never changes the trust score.
Captured 5 Nov 2026 · Analysed npm/@pipeworx/mcp-chembl@0.2.1
Provenance Verified
A signed build attestation was found and verified, binding this exact artifact to the source repository it claims to come from.
| Result | Verified |
|---|---|
| Ecosystem | npm |
| Reason | Verified |
| Discovered via | Registry attestation endpoint |
| Source repo | pipeworx-io/mcp-chembl |
| Certificate issuer | https://token.actions.githubusercontent.com |
| Certificate SAN | https://github.com/pipeworx-io/mcp-chembl/.github/workflows/publish.yml@refs/heads/main |
| Rekor log index | 3606747444 |
| Predicate type | SLSA build provenance https://slsa.dev/provenance/v1 |
| Subject digest | sha512:a556b1b04f6161ff25100fb474f913938310688662afe6e9c773fa0a8786fa3b55ff270ce5d6f135732d9f7d638d9c94e1c658f5af78ed1905017724e |
Background: How many MCP packages publish verified provenance →
Dependencies 0 packages
| Packages resolved | 0 |
|---|---|
| Tree resolution | Complete |
Background: SBOMs and build attestations, explained →
The tools this component advertises to a client, with an estimated token cost for each. Expand a tool to see its parameters and schema. The per-tool counts are indicative and are not scored directly; the schema's total context footprint is one signal in Schema Quality & AI Usability. A tool's description is untrusted text the model reads on every call, which is what makes this list a security surface and not just an inventory: how tool poisoning works →
activities ~119
Retrieve bioactivity records from ChEMBL filtered by molecule_chembl_id and/or target_chembl_id; returns IC50/Ki/EC50 values, assay descriptions, and units. This is SMALL-MOLECULE assay data: a biologic such as an antibody has none by construction, and the response says so rather than returning a bare empty list.
| Name | Type | Req | Description |
|---|---|---|---|
| limit | number | – | 1-1000 (default 25). |
| molecule_chembl_id | string | – | – |
| target_chembl_id | string | – | – |
No output schema declared.
No examples provided.
chembl_mechanism ~470
Mechanism of action of a drug, from its NAME (or a ChEMBL molecule ID). Answers "how does metformin work", "what is the mechanism of action of X", "what does X inhibit", "what target does X act on", "X mode of action", "is X an agonist or an antagonist", "X molecular target". Resolves the drug name to every matching ChEMBL molecule form — the base compound together with its salts, hydrochlorides, mesylates and branded formulations — and searches all of them at once, so a drug whose pharmacology is curated on the salt form still resolves. Returns, per mechanism: action_type (INHIBITOR, AGONIST, ANTAGONIST, BLOCKER, MODULATOR, ...), the mechanism_of_action sentence (e.g. "Mitochondrial complex I (NADH dehydrogenase) inhibitor"), the molecular target with its ChEMBL target ID, target name and organism, the exact molecule form the mechanism is recorded on with its preferred name, max clinical phase, curator mechanism/selectivity comments, and PubMed references. Also lists every molecule ID searched, so an empty result is interpretable. Curated pharmacology from ChEMBL (EMBL-EBI). Reach for this for pharmacology, mode of action, drug-target identification, and any "how does this drug work" question.
| Name | Type | Req | Description |
|---|---|---|---|
| candidates | number | – | How many name-matched molecule forms to search across, 1-25 (default 10). Higher catches obscure salt forms. |
| chembl_id | string | – | Alias for molecule_chembl_id. |
| drug | string | – | Drug name, e.g. "metformin", "imatinib", "aspirin". Brand, generic, or salt names all work. |
| limit | number | – | Max mechanisms returned, 1-200 (default 50). |
| molecule_chembl_id | string | – | Exact ChEMBL molecule ID instead of a name, e.g. "CHEMBL1431". Salt forms of this molecule are included automatically. |
| name | string | – | Alias for drug. |
| q | string | – | Alias for drug. |
| query | string | – | Alias for drug. |
No output schema declared.
No examples provided.
drug_indications ~75
Retrieve approved drug indication records from ChEMBL filtered by molecule_chembl_id and/or MeSH disease ID; returns disease names, efo_id cross-references, and max clinical trial phase.
| Name | Type | Req | Description |
|---|---|---|---|
| limit | number | – | – |
| mesh_id | string | – | – |
| molecule_chembl_id | string | – | – |
No output schema declared.
No examples provided.
mechanism ~85
Raw ChEMBL mechanism records for one exact molecule ChEMBL ID (e.g. "CHEMBL1703"), returned verbatim from the API. Use when you already hold the precise molecule ID and want the unshaped rows; to start from a drug name, call `chembl_mechanism`.
| Name | Type | Req | Description |
|---|---|---|---|
| chembl_id | string | yes | molecule_chembl_id |
No output schema declared.
No examples provided.
molecule ~37
Full molecule record by ChEMBL ID (e.g. "CHEMBL25" = aspirin).
| Name | Type | Req | Description |
|---|---|---|---|
| chembl_id | string | yes | – |
No output schema declared.
No examples provided.
search ~118
Full-text search the ChEMBL drug-discovery database for molecules, targets, assays, or documents; returns ChEMBL IDs and summary fields you can pass to `molecule`, `target`, or `activities`. Pair with `chembl_mechanism`, which takes a drug name directly and returns its mechanism of action and target.
| Name | Type | Req | Description |
|---|---|---|---|
| limit | number | – | 1-1000 (default 25). |
| query | string | yes | Free-text query. |
| type | string | – | molecule (default) | target | assay | document |
No output schema declared.
No examples provided.
target ~25
Target record by ChEMBL target ID.
| Name | Type | Req | Description |
|---|---|---|---|
| chembl_id | string | yes | – |
No output schema declared.
No examples provided.
How do I install the Chembl MCP server?
Chembl runs locally as an npm package, launched with npx -y @pipeworx/mcp-chembl. Ready-made configuration for Claude, Cursor, VS Code, Codex and 5 more is on this page, copied from each client's own documentation.
npm · @pipeworx/mcp-chembl
claude mcp add pipeworx-io-chembl -- npx -y @pipeworx/mcp-chembl
What is the Chembl MCP server?
Chembl is an MCP server listed in the public MCP registry as io.github.pipeworx-io/chembl. ChEMBL MCP, drug discovery database (EBI). This page covers its npm package (@pipeworx/mcp-chembl).
Is the Chembl MCP server safe to use?
Chembl scores 82 out of 100 on VerifyMCP. We found no known CVEs affecting it as of 5 November 2026. It declares no install or post-install scripts. Its build provenance is signed and verified. That is a record of what we were able to check automatically, not an endorsement. The category breakdown on this page shows every signal behind the number, including the ones we could not confirm.
What tools does the Chembl MCP server expose?
Chembl exposes 7 tools: search, molecule, target, mechanism, chembl_mechanism, and 2 more. Their descriptions and schemas cost roughly 929 tokens of context every time the server is loaded.
Is the Chembl MCP server still maintained?
Chembl is still listed as active in the MCP registry. We last reached this channel on 5 November 2026. Those dates come from our own scans of the registry and the channel itself, not from anything the publisher announced.
What licence is the Chembl MCP server under?
Chembl declares the MIT licence, which is OSI-approved. That covers the source only, and says nothing about the cost of any service it calls.