BioCosm
REMOTE · BIOCOSM-MCP.FLY.DEV · SCANNED SEP 22
Biotech intelligence for AI agents: drugs, targets, diagnostics, PoS estimates, and writeups.
Available components
How this component scores in each security and reliability category. Every signal is checked automatically against the live server, and we only credit what we can confirm. How we score → Why this is hard to score →
Endpoint Security57
- The endpoint's TLS certificate is valid, in date, and uses a strong key. View diagnostics → Pass
- Authorisation not fully verified: no authorisation is required to call this server, and 13 tool(s) never declared a destructiveHint. The MCP spec treats an absent hint as destructive by default, so we cannot call this surface safe. See how to fix → View diagnostics → Unverified
- HTTPS is enforced; there's no plaintext access path. View diagnostics → Pass
- HSTS check failed: the Strict-Transport-Security header is absent. See how to fix → View diagnostics → Fail
- DNSSEC check failed: this domain isn't protected by DNSSEC. See how to fix → View diagnostics → Fail
Transport & Reachability100
- Verified streamable-http transport via a live MCP handshake. View diagnostics → Pass
Schema Quality & AI Usability83
- AI-judged instruction clarity (excellent).Pass
- Tool/resource definitions use about 1284 tokens (~98/item across 13 items; 13 tools + 0 resources), lean.Pass
- Usage-examples check failed: none of the tools include examples. See how to fix → Fail
Stability & Change Management100
- No destabilizing schema changes in the last 30 days.Pass
Tool Coverage100
- 100% of tools have a non-trivial description (not blank, and not just the tool's name).Pass
- 100% of tool parameters carry a description.Pass
- Structured output schemas are declared (100% of tools); any adoption earns full credit.Pass
Tool Safety100
- No prompt-injection markers were found in the server instructions, tool names or descriptions we captured.Pass
- We read all 13 captured tool definition(s), and no name or description among them implies an irreversible operation.Pass
- An AI judge read all 14 captured unit(s) of tool text and found none that tries to manipulate the model reading it.Pass
Capabilities100
- Implements a supported MCP spec version (2025-11-25); the latest is 2026-07-28.Pass
How do I install the BioCosm MCP server?
BioCosm is a hosted endpoint at https://biocosm-mcp.fly.dev/mcp, so there is nothing to install locally. Ready-made configuration for Claude, Cursor, VS Code, Codex and 5 more is on this page, copied from each client's own documentation.
remote · biocosm-mcp.fly.dev
claude mcp add --transport http nhoverte-biocosm 'https://biocosm-mcp.fly.dev/mcp'
{
"mcpServers": {
"nhoverte-biocosm": {
"url": "https://biocosm-mcp.fly.dev/mcp"
}
}
} {
"servers": {
"nhoverte-biocosm": {
"type": "http",
"url": "https://biocosm-mcp.fly.dev/mcp"
}
}
} [mcp_servers.nhoverte-biocosm] url = "https://biocosm-mcp.fly.dev/mcp"
{
"$schema": "https://opencode.ai/config.json",
"mcp": {
"nhoverte-biocosm": {
"type": "remote",
"url": "https://biocosm-mcp.fly.dev/mcp",
"enabled": true
}
}
} openclaw mcp add nhoverte-biocosm --url 'https://biocosm-mcp.fly.dev/mcp' --transport streamable-http
mcp_servers:
nhoverte-biocosm:
url: "https://biocosm-mcp.fly.dev/mcp" {
"McpServers": {
"nhoverte-biocosm": {
"Transport": "http",
"Url": "https://biocosm-mcp.fly.dev/mcp"
}
}
} assistant mcp add nhoverte-biocosm -t streamable-http -u 'https://biocosm-mcp.fly.dev/mcp'
{
"mcpServers": {
"nhoverte-biocosm": {
"type": "http",
"url": "https://biocosm-mcp.fly.dev/mcp"
}
}
} The mcpServers block is a cross-client convention. Remote transports vary, so check your client's docs.
Every change we have recorded for this component, newest first. Security-relevant changes are always shown. ▲ marks a change for the better, ▼ a change for the worse; unmarked changes are neutral.
- 17 Sept 26 0
- HSTS header: unverified → fail ▼ security
- Injection markers: unverified → pass ▲ security
- Stability: unverified → pass ▲ security
- Transport: fail → pass ▲ security
- Authorization: Authorisation not fully verified: no authorisation is required to call this server, and 13 tool(s) never declared a destructiveHint. The MCP spec treats an absent hint as destructive by default, so we cannot call this surface safe. security
- Endpoint reachability: unreachable → reachable ▲ functional
- Tool coverage: unverified → 100 ▲ functional
- MCP protocol: unverified → pass ▲ functional
- 16 Sept 26 0
- Endpoint reachability: reachable → unreachable ▼ security
- HSTS header: fail → unverified ▼ security
- Stability: pass → unverified ▼ security
- Tool safety: pass → unverified ▼ security
- Transport: pass → fail ▼ security
- Authorization: Authorisation not yet verified: we couldn't confirm whether this endpoint requires it. security
- Capabilities: pass → unverified ▼ functional
- Tool coverage: 100 → unverified ▼ functional
- 28 Aug 26 0
- HSTS header: unverified → fail ▼ security
- Injection markers: unverified → pass ▲ security
- Stability: unverified → pass ▲ security
- Transport: fail → pass ▲ security
- Authorization: Authorisation not fully verified: no authorisation is required to call this server, and 13 tool(s) never declared a destructiveHint. The MCP spec treats an absent hint as destructive by default, so we cannot call this surface safe. security
- Endpoint reachability: unreachable → reachable ▲ functional
- Tool coverage: unverified → 100 ▲ functional
- MCP protocol: unverified → pass ▲ functional
- 27 Aug 26 0
- Endpoint reachability: reachable → unreachable ▼ security
- HSTS header: fail → unverified ▼ security
- Stability: pass → unverified ▼ security
- Tool safety: pass → unverified ▼ security
- Transport: pass → fail ▼ security
- Authorization: Authorisation not yet verified: we couldn't confirm whether this endpoint requires it. security
- Capabilities: pass → unverified ▼ functional
- Tool coverage: 100 → unverified ▼ functional
- First check of Schema quality: unverified functional
- 26 Aug 26 +1
- We updated how we score, so this day's move reflects our rubric, not a change to the server See what changed → functional
- 25 Aug 26 0
- Stability: 0.97 → pass security
- 11 Aug 26 0
- We updated how we score, so this day's move reflects our rubric, not a change to the server See what changed → functional
- 7 Aug 26 0
- The server no longer declares the “experimental” capability functional
Diagnostic detail from the automated scan of this channel: what the scanner observed at each step, so you can see exactly where a check passed or failed. It is informational only and never changes the trust score.
Captured 22 Sept 2026 · Probed https://biocosm-mcp.fly.dev/mcp
TLS valid
Negotiated TLS 1.3 with TLS_AES_128_GCM_SHA256 .
| Subject | Issuer | Valid from | Valid until | Key | Signature | Serial |
|---|---|---|---|---|---|---|
| CN=*.fly.dev | CN=YE1,O=Let's Encrypt,C=US | 21 Aug 2026 | 19 Nov 2026 | ECDSA 256 | ECDSA-SHA384 | 688c4daf5300c51e0a5c1f6837a3a67a868 |
| SANs: *.fly.dev | ||||||
| CN=YE1,O=Let's Encrypt,C=US (CA) | CN=Root YE,O=ISRG,C=US | 3 Sept 2025 | 2 Sept 2028 | ECDSA 384 | ECDSA-SHA384 | 5ddd70dd31f801c85c186a7a04b80afe |
| CN=Root YE,O=ISRG,C=US (CA) | CN=ISRG Root X2,O=Internet Security Research Group,C=US | 13 May 2026 | 2 Sept 2032 | ECDSA 384 | ECDSA-SHA384 | 872165fc34b6e5fba8add5b3705fb53a |
| CN=ISRG Root X2,O=Internet Security Research Group,C=US (CA) | CN=ISRG Root X1,O=Internet Security Research Group,C=US | 13 May 2026 | 2 Sept 2032 | ECDSA 384 | SHA256-RSA | 6c8f1dc727c7117f7baf853ac980f9cd |
Background: What to check on a remote MCP endpoint →
DNSSEC insecure
Validation of biocosm-mcp.fly.dev. — Not signed
| Zone | DS | Keys | Algorithms | Outcome |
|---|---|---|---|---|
| . | trust_anchor | 20326, 38696 | 8, 8 | Verified |
| dev. | present | 60074 | 8 | Verified |
| fly.dev. | absent | Unsigned (proven) parent-signed NSEC/NSEC3 proves an unsigned delegation |
Authentication No authorisation required
The endpoint answered without asking for a token. Anyone who knows the URL can reach it.
| Result | No authorisation required |
|---|---|
| HTTP status | 200 |
Background: How OAuth 2.1 works in the 2026 MCP spec →
Transports 2 probes
| Transport | URL | Outcome | Status | Location |
|---|---|---|---|---|
| streamable-http | https://biocosm-mcp.fly.dev/mcp | Verified | 200 | |
| http (plaintext) | http://biocosm-mcp.fly.dev/mcp | HTTPS enforced | 301 | https://biocosm-mcp.fly.dev/mcp |
The tools this component advertises to a client, with an estimated token cost for each. Expand a tool to see its parameters and schema. The per-tool counts are indicative and are not scored directly; the schema's total context footprint is one signal in Schema Quality & AI Usability. A tool's description is untrusted text the model reads on every call, which is what makes this list a security surface and not just an inventory: how tool poisoning works →
find_by_phase ~102
List drugs/diagnostics at a specific clinical phase.
| Name | Type | Req | Description |
|---|---|---|---|
| limit | integer | – | Maximum results (default 100, max 500) |
| node_type | – | – | Optional filter — "drug", "pipeline", "diagnostic", "target" |
| phase | string | yes | One of "approved", "on_market", "phase3", "phase2", "phase1", "in_development", "cleared", "ldt", "ruo" |
| Name | Type | Req | Description |
|---|---|---|---|
| result | array | yes | – |
No examples provided.
find_by_target ~66
Find all drugs that target a specific gene/protein.
| Name | Type | Req | Description |
|---|---|---|---|
| limit | integer | – | Maximum results (default 50, max 200) |
| target_gene | string | yes | Gene symbol or target name (e.g. "EGFR", "KRAS", "PD-1") |
| Name | Type | Req | Description |
|---|---|---|---|
| result | array | yes | – |
No examples provided.
find_related ~145
Find nodes connected to a given node. Three relationship types are derived on-the-fly: - "drug_target": for a drug, the targets it hits (and vice versa for a target node, the drugs that hit it) - "same_company": drugs sharing a company with this node - "same_target_class": drugs with the same mechanism_class
| Name | Type | Req | Description |
|---|---|---|---|
| limit | integer | – | Maximum results per link type (default 30) |
| link_type | – | – | Optional filter — one of "drug_target", "same_target_class", "same_company". If None, returns all three groups. |
| node_id | string | yes | Source node identifier |
| Name | Type | Req | Description |
|---|---|---|---|
| result | – | yes | – |
No examples provided.
get_company_portfolio ~50
Get a company's full drug/diagnostic portfolio from BioCosm.
| Name | Type | Req | Description |
|---|---|---|---|
| company_name | string | yes | Company name (e.g. "Merck", "Roche", "Illumina") |
| Name | Type | Req | Description |
|---|---|---|---|
| result | – | yes | – |
No examples provided.
get_coverage ~65
Report BioCosm's actual data coverage so you never mistake missing data for a real-world zero. An empty or absent field on a node means "not in BioCosm's data," never a true zero. BioCosm is AI-generated and may contain errors.
Input schema present but exposes no named parameters.
Structured output declared, but exposes no named fields.
No examples provided.
get_node ~145
Get full details for a single BioCosm node: identity and all name aliases, classification, gene targets and mechanism, therapeutic areas, companies, revenue history where available (sparse: ~100 drugs, mostly blockbusters, as annualized quarterly estimates; source links when present), probability-of- success predictions for pipeline drugs (with confidence intervals and contributing factors), structured clinical trial outcomes, external cross-references, and writeup availability. Empty fields mean "not in BioCosm's coverage," NOT zero or absent in reality.
| Name | Type | Req | Description |
|---|---|---|---|
| node_id | string | yes | The node identifier (e.g. "pembrolizumab", "trastuzumab") |
| Name | Type | Req | Description |
|---|---|---|---|
| result | – | yes | – |
No examples provided.
get_node_freshness ~56
Get freshness details for a single node: writeup age, enrichment hash match, staleness score, validation score.
| Name | Type | Req | Description |
|---|---|---|---|
| node_id | string | yes | The node identifier (e.g. "pembrolizumab") |
| Name | Type | Req | Description |
|---|---|---|---|
| result | – | yes | – |
No examples provided.
get_pos_score ~68
Get the Probability of Success estimate for a node, including the base rate, adjustment factors with reasoning, confidence interval, and model version. Returns None for nodes without a PoS score (typically only late-stage pipeline drugs are scored).
| Name | Type | Req | Description |
|---|---|---|---|
| node_id | string | yes | Node identifier |
| Name | Type | Req | Description |
|---|---|---|---|
| result | – | yes | – |
No examples provided.
get_staleness_report ~48
Get writeup staleness report: overall stats, top stale nodes, data source freshness.
| Name | Type | Req | Description |
|---|---|---|---|
| limit | integer | – | Number of top stale nodes to return (default 20) |
Structured output declared, but exposes no named fields.
No examples provided.
get_stats ~44
Get a high-level overview of the BioCosm database: total nodes, writeups, companies, breakdowns by type/status/domain, validation scores, and recent pipeline runs.
Input schema present but exposes no named parameters.
Structured output declared, but exposes no named fields.
No examples provided.
get_writeup ~55
Get the full writeup for a BioCosm node, including all sections, citations, structured data, and validation score.
| Name | Type | Req | Description |
|---|---|---|---|
| node_id | string | yes | The node identifier (e.g. "pembrolizumab") |
| Name | Type | Req | Description |
|---|---|---|---|
| result | – | yes | – |
No examples provided.
list_by_therapeutic_area ~62
List all nodes in a given therapeutic area.
| Name | Type | Req | Description |
|---|---|---|---|
| area | string | yes | Therapeutic area to search (e.g. "breast cancer", "non-small cell lung cancer") |
| limit | integer | – | Maximum results (default 50) |
| Name | Type | Req | Description |
|---|---|---|---|
| result | array | yes | – |
No examples provided.
search_nodes ~146
Search BioCosm nodes by name, gene symbol, target, therapeutic area, or company. Results are ranked: exact name/brand matches first, then partial name matches, with a node-type prior (canonical drug/diagnostic nodes rank above gene-target nodes, which rank above ChEMBL salt-form duplicates). Nodes matched only via description/company/area rank last. Each result includes a `name` field for disambiguation.
| Name | Type | Req | Description |
|---|---|---|---|
| limit | integer | – | Maximum results to return (default 20, max 100) |
| query | string | yes | Search term (e.g. "breast cancer", "pembrolizumab", "Merck") |
| Name | Type | Req | Description |
|---|---|---|---|
| result | array | yes | – |
No examples provided.
What is the BioCosm MCP server?
BioCosm is an MCP server listed in the public MCP registry as io.github.nhoverte/biocosm. Biotech intelligence for AI agents: drugs, targets, diagnostics, PoS estimates, and writeups. This page covers its hosted endpoint (https://biocosm-mcp.fly.dev/mcp).
Is the BioCosm MCP server safe to use?
BioCosm scores 80 out of 100 on VerifyMCP. That is a record of what we were able to check automatically, not an endorsement. The category breakdown on this page shows every signal behind the number, including the ones we could not confirm.
What tools does the BioCosm MCP server expose?
BioCosm exposes 13 tools: search_nodes, get_node, get_writeup, list_by_therapeutic_area, get_company_portfolio, and 8 more. Their descriptions and schemas cost roughly 1,052 tokens of context every time the server is loaded.
Does the BioCosm MCP server require authentication?
No. We connected to BioCosm without credentials and it answered, so anything it exposes is reachable by anyone who knows the address.
Is the BioCosm MCP server still maintained?
BioCosm is still listed as active in the MCP registry. We last reached this channel on 22 September 2026. Those dates come from our own scans of the registry and the channel itself, not from anything the publisher announced.