{"$schema":"https://verifymcp.io/schemas/trust-report.json","schemaVersion":1,"license":{"name":"CC BY-NC 4.0","url":"https://creativecommons.org/licenses/by-nc/4.0/"},"generatedAt":"2026-11-05T17:28:10.895Z","url":"https://verifymcp.io/servers/pipeworx-io-opentargets/pipeworx-mcp-opentargets","markdownUrl":"https://verifymcp.io/servers/pipeworx-io-opentargets/pipeworx-mcp-opentargets.md","server":{"slug":"pipeworx-io-opentargets","name":"Opentargets","registryName":"io.github.pipeworx-io/opentargets","description":"Open Targets MCP — disease/target/drug knowledge graph.","registryStatus":"active","deletedAt":null,"statusMessage":null,"liveness":"live","publisher":{"class":"unknown","claimed":false}},"component":{"slug":"pipeworx-mcp-opentargets","type":"npm","identifier":"@pipeworx/mcp-opentargets","withdrawn":false,"url":"https://verifymcp.io/servers/pipeworx-io-opentargets/pipeworx-mcp-opentargets","version":"0.2.1","transport":"stdio","scoredAt":"2026-11-05T10:15:28.803Z"},"score":{"total":82,"tier":"high trust","status":"scored","weekDelta":4,"history":[{"date":"2026-11-05","total":82},{"date":"2026-11-04","total":66},{"date":"2026-11-03","total":81},{"date":"2026-11-02","total":80},{"date":"2026-11-01","total":80},{"date":"2026-10-31","total":79},{"date":"2026-10-30","total":79},{"date":"2026-10-29","total":78}]},"categories":[{"name":"Supply Chain Security","score":100,"verdict":"pass","reasons":["No malware found by supply-chain analysis.","No known CVEs affecting this package version or its production dependencies.","No install/post-install scripts declared.","No production dependencies, so there is no dependency health to assess."],"codes":[{"code":"supplychain.malware_clean","args":{}},{"code":"cve.none","args":{}},{"code":"installscript.none","args":{}},{"code":"dephealth.no_dependencies","args":{"deps":"0","unhealthy":"0"}}]},{"name":"Provenance & Transparency","score":97,"verdict":"fail","reasons":["Source repository is publicly reachable at the declared URL.","Cryptographically verified build provenance (signed, bound to pipeworx-io/mcp-opentargets).","Clear OSI-approved license (MIT).","Actively maintained (last published 1 days ago).","Disclosure check failed: no security disclosure policy was found in the source repository."],"codes":[{"code":"provenance.repo_verified","args":{}},{"code":"provenance.verified","args":{"repo":"pipeworx-io/mcp-opentargets"}},{"code":"license.osi","args":{"spdx":"MIT"}},{"code":"maintenance.recent","args":{"age_days":"1"}},{"code":"disclosure.absent","args":{}}]},{"name":"Schema Quality & AI Usability","score":67,"verdict":"fail","reasons":["AI-judged instruction clarity (good).","Tool/resource definitions use about 797 tokens (~113/item across 7 items; 7 tools + 0 resources), lean.","Usage-examples check failed: none of the tools include examples."],"codes":[{"code":"schema.ai_quality","args":{"band":"good"}},{"code":"schema.footprint_lean","args":{"avg":"113","items":"7","tools":"7","tokens":"797","resources":"0"}},{"code":"schema.examples_absent","args":{}}]},{"name":"Stability & Change Management","score":23,"verdict":"partial","reasons":["Stability observed for 7 of 30 days with no destabilising changes; credit accrues until the full window elapses."],"codes":[{"code":"stability.building_history","args":{"days":"7"}}]},{"name":"Tool Coverage","score":86,"verdict":"partial","reasons":["100% of tools have a non-trivial description (not blank, and not just the tool's name).","58% of tool parameters carry a description."],"codes":[{"code":"toolquality.descriptions","args":{"pct":"100"}},{"code":"toolquality.param_docs","args":{"pct":"58"}}]},{"name":"Tool Safety","score":100,"verdict":"pass","reasons":["No prompt-injection markers were found in the server instructions, tool names or descriptions we captured.","We read all 7 captured tool definition(s), and no name or description among them implies an irreversible operation.","An AI judge read all 8 captured unit(s) of tool text and found none that tries to manipulate the model reading it."],"codes":[{"code":"toolsafety.injection_clean","args":{}},{"code":"toolsafety.destructive_none","args":{"tools":"7"}},{"code":"toolsafety.manipulation_clean","args":{"units":"8","judged":"8"}}]},{"name":"Capabilities","score":100,"verdict":"pass","reasons":["Implements a supported MCP spec version (2025-11-25); the latest is 2026-07-28."],"codes":[{"code":"protocol.supported","args":{"latest":"2026-07-28","version":"2025-11-25"}}]}],"inconclusive":[],"malware":[],"components":[{"slug":"opentargets-mcp","type":"remote","identifier":"https://gateway.pipeworx.io/opentargets/mcp","withdrawn":false,"score":77,"current":false,"url":"https://verifymcp.io/servers/pipeworx-io-opentargets/opentargets-mcp","markdownUrl":"https://verifymcp.io/servers/pipeworx-io-opentargets/opentargets-mcp.md"},{"slug":"pipeworx-mcp-opentargets","type":"npm","identifier":"@pipeworx/mcp-opentargets","withdrawn":false,"score":82,"current":true,"url":"https://verifymcp.io/servers/pipeworx-io-opentargets/pipeworx-mcp-opentargets","markdownUrl":"https://verifymcp.io/servers/pipeworx-io-opentargets/pipeworx-mcp-opentargets.md"}],"facts":[{"label":"Registry","value":"npm"},{"label":"Package","value":"@pipeworx/mcp-opentargets"},{"label":"Version","value":"0.2.1"},{"label":"Transport","value":"stdio"}],"install":{"available":true,"bundleSha256":null},"tools":[{"name":"target","title":null,"description":"\"Drug target profile for [gene]\" / \"is [gene] a druggable target\" / \"[gene] target info\" / \"target ID [ENSG...]\" — fetch a drug-target profile (Open Targets uses Ensembl gene IDs as target identifiers). Returns approved symbol, name, biotype, protein IDs, pathways, synonyms. Use for target characterization in drug discovery.","inputs":[{"name":"ensembl_id","type":"string","required":true,"description":"e.g. \"ENSG00000141510\" (TP53)"}],"outputs":[],"hasOutputSchema":false,"hasExamples":false,"tokenEstimate":107},{"name":"disease","title":null,"description":"\"Disease profile for [EFO_N]\" / \"look up disease [ID]\" — fetch a disease profile from Open Targets by EFO (Experimental Factor Ontology) ID. Returns name, description, therapeutic areas, ontology cross-refs. Pair with `disease_associations` to find drug targets for the disease.","inputs":[{"name":"efo_id","type":"string","required":true,"description":"e.g. \"EFO_0000270\" (asthma)"}],"outputs":[],"hasOutputSchema":false,"hasExamples":false,"tokenEstimate":96},{"name":"drug","title":null,"description":"\"Drug info for [ChEMBL ID]\" / \"look up [drug] target info\" / \"[CHEMBL...] mechanism\" — fetch a drug profile from Open Targets by ChEMBL ID. Returns name, mechanisms of action, indications, target genes, trade names, clinical-trial phase. Use for drug research, mechanism queries.","inputs":[{"name":"chembl_id","type":"string","required":true,"description":"e.g. \"CHEMBL1201583\" (imatinib)"}],"outputs":[],"hasOutputSchema":false,"hasExamples":false,"tokenEstimate":101},{"name":"search","title":null,"description":"\"Find [disease / drug / gene target]\" / \"Open Targets lookup for [name]\" / \"what's the Open Targets ID for [X]\" — text search across diseases, drug targets, and drugs in the Open Targets Platform (the leading drug-discovery knowledge graph). Returns ranked matches with their canonical IDs (ENSG... for targets, EFO_... for diseases, CHEMBL... for drugs). Use first to find IDs, then call target/disease/drug for details.","inputs":[{"name":"entity","type":"string","required":false,"description":"target | disease | drug (omit for all)"},{"name":"query","type":"string","required":true,"description":null},{"name":"size","type":"number","required":false,"description":"1-50 (default 10)"}],"outputs":[],"hasOutputSchema":false,"hasExamples":false,"tokenEstimate":146},{"name":"target_associations","title":null,"description":"\"What diseases is [gene] involved in\" / \"diseases associated with [target]\" / \"what does [gene] cause\" — top disease associations for a drug target (Ensembl gene ID), scored by integrated Open Targets evidence (genetics, expression, animal models, drugs, literature, pathways). Use to triage what diseases a candidate target might address.","inputs":[{"name":"ensembl_id","type":"string","required":true,"description":null},{"name":"size","type":"number","required":false,"description":"1-50 (default 10)"}],"outputs":[],"hasOutputSchema":false,"hasExamples":false,"tokenEstimate":109},{"name":"disease_associations","title":null,"description":"\"Best drug targets for [disease]\" / \"what genes are linked to [condition]\" / \"druggable targets in [disease]\" — top drug-target candidates for a disease (EFO ID), scored by integrated evidence. Use for target discovery in a therapeutic area.","inputs":[{"name":"efo_id","type":"string","required":true,"description":null},{"name":"size","type":"number","required":false,"description":null}],"outputs":[],"hasOutputSchema":false,"hasExamples":false,"tokenEstimate":82},{"name":"target_known_drugs","title":null,"description":"\"What drugs target [gene]\" / \"approved drugs against [target]\" / \"clinical-trial drugs for [gene]\" — drugs that have been clinically tested or approved against a drug target (Ensembl gene ID). Returns drug names, mechanisms, indications, clinical trial phases. Use for competitive landscape / drug-repositioning queries.","inputs":[{"name":"ensembl_id","type":"string","required":true,"description":null},{"name":"size","type":"number","required":false,"description":"1-100 (default 25)"}],"outputs":[],"hasOutputSchema":false,"hasExamples":false,"tokenEstimate":101}],"toolsTruncatedAtCapture":false,"diagnostics":{"capturedAt":"2026-11-05T10:15:28.000Z","track":"package","endpoint":null,"declaredUrl":null,"truncated":false,"tls":null,"dnssec":null,"auth":null,"httpsRedirect":null,"transports":[],"provenance":{"outcome":"verified","label":"Verified","reason":"verified","reasonLabel":"Verified","discovery":"attestation_endpoint","discoveryLabel":"Registry attestation 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81)","materiality":"functional","direction":"improvement","scoreDelta":1,"occurredOn":"2026-11-03","url":"https://verifymcp.io/servers/pipeworx-io-opentargets/pipeworx-mcp-opentargets#chg-chg_01a1a0e6-b0cc-7a45-9bcb-e45aa586b285"},{"id":"chg_01a1969a-d388-7d75-a080-9e9a2d204189","kind":"score.total_changed","summary":"Trust score (79 → 80)","materiality":"functional","direction":"improvement","scoreDelta":1,"occurredOn":"2026-11-01","url":"https://verifymcp.io/servers/pipeworx-io-opentargets/pipeworx-mcp-opentargets#chg-chg_01a1969a-d388-7d75-a080-9e9a2d204189"},{"id":"chg_01a18c4d-fdb6-7b0b-ab2d-19076048d3a4","kind":"score.total_changed","summary":"Trust score (78 → 79)","materiality":"functional","direction":"improvement","scoreDelta":1,"occurredOn":"2026-10-30","url":"https://verifymcp.io/servers/pipeworx-io-opentargets/pipeworx-mcp-opentargets#chg-chg_01a18c4d-fdb6-7b0b-ab2d-19076048d3a4"},{"id":"chg_01a18674-0fdd-74ca-9196-b025718a885e","kind":"score.first_scored","summary":"First 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report","href":"https://socket.dev/npm/package/@pipeworx/mcp-opentargets"},{"label":"Repository","href":"https://github.com/pipeworx-io/mcp-opentargets"},{"label":"Website","href":"https://pipeworx.io/packs/opentargets"}]}}