# Civic (npm · @pipeworx/mcp-civic)

CIViC — Clinical Interpretation of Variants in Cancer.

- Trust score: 83/100 (high trust)
- Change this week: +4
- Registry status: active
- Liveness: live
- Owner verified: no
- Last scored: 2026-11-05

## Components

- remote · `gateway.pipeworx.io`: 77/100, [markdown](https://verifymcp.io/servers/pipeworx-io-civic/civic-mcp.md), [page](https://verifymcp.io/servers/pipeworx-io-civic/civic-mcp)
- npm · `@pipeworx/mcp-civic`: 83/100 (this document), [markdown](https://verifymcp.io/servers/pipeworx-io-civic/pipeworx-mcp-civic.md), [page](https://verifymcp.io/servers/pipeworx-io-civic/pipeworx-mcp-civic)

## Channel facts

- Registry: `npm`
- Package: `@pipeworx/mcp-civic`
- Version: `0.2.1`
- Transport: `stdio`

## Trust breakdown

How this component scores in each security and reliability category. Every signal is checked automatically from public evidence about the published package, including repeated runs of it in an isolated sandbox, and we only credit what we can confirm. Scores are 0–100 per category. Scoring method: https://verifymcp.io/docs/scoring (what has changed: https://verifymcp.io/docs/scoring/changelog)

Scored 2026-11-05.

- **Supply Chain Security**: 100/100
  - No malware found by supply-chain analysis.
  - No known CVEs affecting this package version or its production dependencies.
  - No install/post-install scripts declared.
  - No production dependencies, so there is no dependency health to assess.
- **Provenance & Transparency**: 97/100
  - Source repository is publicly reachable at the declared URL.
  - Cryptographically verified build provenance (signed, bound to pipeworx-io/mcp-civic).
  - Clear OSI-approved license (MIT).
  - Actively maintained (last published 5 days ago).
  - Disclosure check failed: no security disclosure policy was found in the source repository.
- **Schema Quality & AI Usability**: 66/100
  - AI-judged instruction clarity (good).
  - Context-footprint check failed: tool/resource definitions use about 759 tokens (~189/item across 4 items; 4 tools + 0 resources), over budget; trim descriptions and params.
  - Usage-examples check failed: none of the tools include examples.
- **Stability & Change Management**: 23/100
  - Stability observed for 7 of 30 days with no destabilising changes; credit accrues until the full window elapses.
- **Tool Coverage**: 100/100
  - 100% of tools have a non-trivial description (not blank, and not just the tool's name).
  - 100% of tool parameters carry a description.
- **Tool Safety**: 100/100
  - No prompt-injection markers were found in the server instructions, tool names or descriptions we captured.
  - We read all 4 captured tool definition(s), and no name or description among them implies an irreversible operation.
  - An AI judge read all 5 captured unit(s) of tool text and found none that tries to manipulate the model reading it.
- **Capabilities**: 100/100
  - Implements a supported MCP spec version (2025-11-25); the latest is 2026-07-28.

## Install

### How do I install the Civic MCP server?

Civic runs locally as an npm package, launched with npx -y @pipeworx/mcp-civic. Ready-made configuration for Claude, Cursor, VS Code, Codex and 5 more is on this page, copied from each client's own documentation.

### Claude

```bash
claude mcp add pipeworx-io-civic -- npx -y @pipeworx/mcp-civic
```

### Cursor

```json
{
  "mcpServers": {
    "pipeworx-io-civic": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-civic"
      ]
    }
  }
}
```

### VS Code

```json
{
  "servers": {
    "pipeworx-io-civic": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-civic"
      ]
    }
  }
}
```

### Codex

```bash
codex mcp add pipeworx-io-civic -- npx -y @pipeworx/mcp-civic
```

### opencode

```json
{
  "$schema": "https://opencode.ai/config.json",
  "mcp": {
    "pipeworx-io-civic": {
      "type": "local",
      "command": [
        "npx",
        "-y",
        "@pipeworx/mcp-civic"
      ],
      "enabled": true
    }
  }
}
```

### OpenClaw

```bash
openclaw mcp add pipeworx-io-civic --command npx --arg -y --arg @pipeworx/mcp-civic
```

### Hermes

```yaml
mcp_servers:
  pipeworx-io-civic:
    command: "npx"
    args: ["-y", "@pipeworx/mcp-civic"]
```

### Netclaw

```json
{
  "McpServers": {
    "pipeworx-io-civic": {
      "Transport": "stdio",
      "Command": "npx",
      "Arguments": [
        "-y",
        "@pipeworx/mcp-civic"
      ]
    }
  }
}
```

### Vellum

```bash
assistant mcp add pipeworx-io-civic -t stdio -c npx -a -y @pipeworx/mcp-civic
```

### Other

```json
{
  "mcpServers": {
    "pipeworx-io-civic": {
      "command": "npx",
      "args": [
        "-y",
        "@pipeworx/mcp-civic"
      ]
    }
  }
}
```

## Changelog

Every change recorded for this component, newest first. Days that predate change tracking, or that we cannot explain, say so: "we were watching and nothing happened" and "we were not watching" are different claims.

### 2026-11-05 (score 83, +1)

No change was recorded against any check on this day. Stability & Change Management went from 20 to 23. That category is still filling its 30-day observation window: 6 days of observed history at the previous scan, 7 at this one. The score rises as the window fills, whether or not the server changes.

### 2026-11-03 (score 82, +1)

No change was recorded against any check on this day. Stability & Change Management went from 13 to 17. That category is still filling its 30-day observation window: 4 days of observed history at the previous scan, 5 at this one. The score rises as the window fills, whether or not the server changes.

### 2026-11-01 (score 81, +1)

- [functional regression] Security disclosure: unverified → fail

### 2026-10-31 (score 80, 0)

- [functional regression] Security disclosure: fail → unverified
- [functional] Package version: 0.2.0 → 0.2.1

### 2026-10-30 (score 80, +1)

No change was recorded against any check on this day. Stability & Change Management went from 0 to 3. That category is still filling its 30-day observation window: 0 days of observed history at the previous scan, 1 at this one. The score rises as the window fills, whether or not the server changes.

### 2026-10-29 (score 79)

First indexed and scored.

## MCP tools (4)

### `civic_search_genes` (~142 tokens)

Find cancer genes and fusions in CIViC by name or symbol, with how much curated clinical evidence each carries (variant count, evidence-item count, assertion count). AUTHORITATIVE starting point for "what does CIViC know about gene X" — CIViC is the open expert-curated knowledgebase of clinically actionable somatic cancer variants. Returns the numeric CIViC feature id you pass to the other tools.

Input parameters:

- `limit` (number): Max features to return, 1-100 (default 25)
- `query` (string, required): Gene symbol or partial name (e.g. "BRAF", "EGFR", "ALK")

### `civic_gene_variants` (~130 tokens)

Curated variants of a cancer gene in CIViC — the specific alterations (missense, fusion, amplification, exon-level) that have published clinical interpretations, each with its evidence count, associated diseases and therapies. AUTHORITATIVE for "which variants of this gene are clinically actionable". Pass the gene symbol.

Input parameters:

- `gene` (string, required): Gene symbol (e.g. "BRAF")
- `limit` (number): Max variants to return, 1-100 (default 25)
- `variant_name` (string): Optional substring filter on the variant name (e.g. "V600")

### `civic_variant_evidence` (~275 tokens)

Individual CIViC evidence items for a molecular profile — the graded, source-linked statements that a variant predicts response or resistance to a therapy, carries prognostic or diagnostic weight, or is oncogenic. Each item carries evidence type, level (A-E), direction, significance, 1-5 star rating, disease, therapies and the PubMed/ASCO source. AUTHORITATIVE for the clinical evidence behind a variant claim, rather than a summary of it. Pass a molecular profile name such as "BRAF V600E", or a numeric CIViC variant id.

Input parameters:

- `disease` (string): Filter by disease name substring (e.g. "Melanoma")
- `evidence_type` (string): Filter: PREDICTIVE | DIAGNOSTIC | PROGNOSTIC | PREDISPOSING | ONCOGENIC | FUNCTIONAL
- `limit` (number): Max evidence items to return, 1-100 (default 25)
- `molecular_profile` (string): Molecular profile name, e.g. "BRAF V600E" or "EGFR L858R"
- `therapy` (string): Filter by therapy name substring (e.g. "Vemurafenib")
- `variant_id` (number): Numeric CIViC variant id (alternative to molecular_profile)

### `civic_assertions` (~161 tokens)

CIViC assertions — the curated, AMP/ASCO/CAP-tiered and ACMG-classified clinical summaries that roll up multiple evidence items into a single actionable statement, including FDA companion-test and regulatory-approval flags. AUTHORITATIVE for "is this variant clinically actionable in this disease, and at what tier". Filter by molecular profile, disease or therapy.

Input parameters:

- `disease` (string): Disease name substring (e.g. "Melanoma")
- `limit` (number): Max assertions to return, 1-100 (default 25)
- `molecular_profile` (string): Molecular profile name, e.g. "BRAF V600E"
- `therapy` (string): Therapy name substring (e.g. "Vemurafenib")

## Diagnostics

Captured diagnostic sections: Provenance, Dependencies. The full working is on the page: https://verifymcp.io/servers/pipeworx-io-civic/pipeworx-mcp-civic#diagnostics

## Score history

- 2026-11-05: 83
- 2026-11-04: 82
- 2026-11-03: 82
- 2026-11-02: 81
- 2026-11-01: 81
- 2026-10-31: 80
- 2026-10-30: 80
- 2026-10-29: 79

## Common questions

### What is the Civic MCP server?

Civic is an MCP server listed in the public MCP registry as io.github.pipeworx-io/civic. CIViC, Clinical Interpretation of Variants in Cancer. This page covers its npm package (@pipeworx/mcp-civic).

### Is the Civic MCP server safe to use?

Civic scores 83 out of 100 on VerifyMCP. We found no known CVEs affecting it as of 5 November 2026. It declares no install or post-install scripts. Its build provenance is signed and verified. That is a record of what we were able to check automatically, not an endorsement. The category breakdown on this page shows every signal behind the number, including the ones we could not confirm.

### What tools does the Civic MCP server expose?

Civic exposes 4 tools: civic_search_genes, civic_gene_variants, civic_variant_evidence, civic_assertions. Their descriptions and schemas cost roughly 708 tokens of context every time the server is loaded.

### Is the Civic MCP server still maintained?

Civic is still listed as active in the MCP registry. We last reached this channel on 5 November 2026. Those dates come from our own scans of the registry and the channel itself, not from anything the publisher announced.

### What licence is the Civic MCP server under?

Civic declares the MIT licence, which is OSI-approved. That covers the source only, and says nothing about the cost of any service it calls.

## Links

- npm package: https://www.npmjs.com/package/@pipeworx/mcp-civic
- Socket report: https://socket.dev/npm/package/@pipeworx/mcp-civic
- Repository: https://github.com/pipeworx-io/mcp-civic
- Website: https://pipeworx.io/packs/civic
- Changelog RSS feed: https://verifymcp.io/servers/pipeworx-io-civic/pipeworx-mcp-civic.xml
- Changelog JSON feed: https://verifymcp.io/servers/pipeworx-io-civic/pipeworx-mcp-civic.json
- HTML version of this page: https://verifymcp.io/servers/pipeworx-io-civic/pipeworx-mcp-civic