# Prognyx oncology intelligence (remote · www.prognyx.com)

Live ClinicalTrials.gov oncology trial comparison around an asset, plus landscapes and CI briefings.

- Trust score: 77/100 (medium)
- Change this week: +3
- Registry status: active
- Liveness: live
- Owner verified: no
- Last scored: 2026-10-07

## Components

- remote · `www.prognyx.com`: 77/100 (this document), [markdown](https://verifymcp.io/servers/com-prognyx-oncology-intelligence/api-mcp.md), [page](https://verifymcp.io/servers/com-prognyx-oncology-intelligence/api-mcp)

## Channel facts

- Endpoint: `https://www.prognyx.com/api/mcp`
- Transports: `streamable-http`
- Auth: `none`
- Version: `1.0.0`

## Trust breakdown

How this component scores in each security and reliability category. Every signal is checked automatically against the live server, and we only credit what we can confirm. Scores are 0–100 per category. Scoring method: https://verifymcp.io/docs/scoring (what has changed: https://verifymcp.io/docs/scoring/changelog)

Scored 2026-10-07.

- **Endpoint Security**: 80/100
  - The endpoint's TLS certificate is valid, in date, and uses a strong key.
  - No authorisation is required to call this server. Every tool declares its destructiveHint and none is destructive, so open access doesn't expose one.
  - HTTPS is enforced; there's no plaintext access path.
  - The HSTS (Strict-Transport-Security) header is present.
  - DNSSEC check failed: this domain isn't protected by DNSSEC.
- **Transport & Reachability**: 100/100
  - Verified streamable-http transport via a live MCP handshake.
- **Schema Quality & AI Usability**: 80/100
  - AI-judged instruction clarity (excellent).
  - Context-footprint check failed: tool/resource definitions use about 436 tokens (~145/item across 3 items; 3 tools + 0 resources), over budget; trim descriptions and params.
  - Usage-examples check failed: none of the tools include examples.
- **Stability & Change Management**: 30/100
  - Stability observed for 9 of 30 days with no destabilising changes; credit accrues until the full window elapses.
- **Tool Coverage**: 100/100
  - 100% of tools have a non-trivial description (not blank, and not just the tool's name).
  - 100% of tool parameters carry a description.
- **Tool Safety**: 100/100
  - No prompt-injection markers were found in the server instructions, tool names or descriptions we captured.
  - We read all 3 captured tool definition(s), and no name or description among them implies an irreversible operation.
  - An AI judge read all 4 captured unit(s) of tool text and found none that tries to manipulate the model reading it.
- **Capabilities**: 60/100
  - Spec-recency check failed: implements MCP spec 2025-06-18; the latest is 2026-07-28.

## Install

### How do I install the Prognyx oncology intelligence MCP server?

Prognyx oncology intelligence is a hosted endpoint at https://www.prognyx.com/api/mcp, so there is nothing to install locally. Ready-made configuration for Claude, Cursor, VS Code, Codex and 5 more is on this page, copied from each client's own documentation.

### Claude

```bash
claude mcp add --transport http com-prognyx-oncology-intelligence 'https://www.prognyx.com/api/mcp'
```

### Cursor

```json
{
  "mcpServers": {
    "com-prognyx-oncology-intelligence": {
      "url": "https://www.prognyx.com/api/mcp"
    }
  }
}
```

### VS Code

```json
{
  "servers": {
    "com-prognyx-oncology-intelligence": {
      "type": "http",
      "url": "https://www.prognyx.com/api/mcp"
    }
  }
}
```

### Codex

```toml
[mcp_servers.com-prognyx-oncology-intelligence]
url = "https://www.prognyx.com/api/mcp"
```

### opencode

```json
{
  "$schema": "https://opencode.ai/config.json",
  "mcp": {
    "com-prognyx-oncology-intelligence": {
      "type": "remote",
      "url": "https://www.prognyx.com/api/mcp",
      "enabled": true
    }
  }
}
```

### OpenClaw

```bash
openclaw mcp add com-prognyx-oncology-intelligence --url 'https://www.prognyx.com/api/mcp' --transport streamable-http
```

### Hermes

```yaml
mcp_servers:
  com-prognyx-oncology-intelligence:
    url: "https://www.prognyx.com/api/mcp"
```

### Netclaw

```json
{
  "McpServers": {
    "com-prognyx-oncology-intelligence": {
      "Transport": "http",
      "Url": "https://www.prognyx.com/api/mcp"
    }
  }
}
```

### Vellum

```bash
assistant mcp add com-prognyx-oncology-intelligence -t streamable-http -u 'https://www.prognyx.com/api/mcp'
```

### Other

```json
{
  "mcpServers": {
    "com-prognyx-oncology-intelligence": {
      "type": "http",
      "url": "https://www.prognyx.com/api/mcp"
    }
  }
}
```

The mcpServers block is a cross-client convention. Remote transports vary, so check your client's docs.

## Changelog

Every change recorded for this component, newest first. Days that predate change tracking, or that we cannot explain, say so: "we were watching and nothing happened" and "we were not watching" are different claims.

### 2026-10-06 (score 77, +1)

No change was recorded against any check on this day. Stability & Change Management went from 20 to 27. That category is still filling its 30-day observation window: 6 days of observed history at the previous scan, 8 at this one. The score rises as the window fills, whether or not the server changes.

### 2026-10-04 (score 76, +1)

No change was recorded against any check on this day. Stability & Change Management went from 17 to 20. That category is still filling its 30-day observation window: 5 days of observed history at the previous scan, 6 at this one. The score rises as the window fills, whether or not the server changes.

### 2026-10-02 (score 75, +1)

No change was recorded against any check on this day. Stability & Change Management went from 10 to 13. That category is still filling its 30-day observation window: 3 days of observed history at the previous scan, 4 at this one. The score rises as the window fills, whether or not the server changes.

### 2026-09-30 (score 74, +1)

No change was recorded against any check on this day. Stability & Change Management went from 3 to 7. That category is still filling its 30-day observation window: 1 days of observed history at the previous scan, 2 at this one. The score rises as the window fills, whether or not the server changes.

### 2026-09-29 (score 73, 0)

- [functional improvement] Stability: unverified → 0.03

### 2026-09-28 (score 73)

First indexed and scored.

## MCP tools (3)

### `compare_trials` (~145 tokens)

Compare trials around an asset

Up to three interventional ClinicalTrials.gov studies matching an asset or target AND an oncology indication, side by side: sponsor, phase, status, declared arms, primary outcomes, last update, registry URL. Active studies first, then later phase; different sponsors where possible. Use a target (e.g. "KIF18A", "B7-H3") rather than one drug name to see other programmes.

Input parameters:

- `asset` (string, required): Public asset or target, e.g. "sotorasib", "KRAS G12C", "B7-H3".
- `indication` (string, required): Oncology indication, e.g. "colorectal cancer", "NSCLC".

### `search_registry` (~116 tokens)

Search the oncology trial registry

Live landscape for a target, asset, company, indication or NCT number: total and active study counts, leading sponsors, phase mix, the most recently updated studies with URLs, and related Prognyx briefings. Counts for phases and sponsors come from a recent sample, stated in the result.

Input parameters:

- `limit` (integer): Studies to return.
- `query` (string, required): e.g. "KRAS G12C", "Nuvalent", "claudin 18.2 gastric cancer", "NCT05132075".

### `search_briefings` (~78 tokens)

Search Prognyx briefings

Prognyx oncology competitive-intelligence briefings (each claim linked to a primary source) matching a drug, company, target or indication, newest first, with URL, date and summary.

Input parameters:

- `limit` (integer): Briefings to return.
- `query` (string): Drug, company, target or indication. Empty returns the latest.

## Diagnostics

Captured diagnostic sections: TLS, DNSSEC, Authorisation, Transports. The full working is on the page: https://verifymcp.io/servers/com-prognyx-oncology-intelligence/api-mcp#diagnostics

## Score history

- 2026-10-07: 77
- 2026-10-06: 77
- 2026-10-04: 76
- 2026-10-03: 75
- 2026-10-02: 75
- 2026-10-01: 74
- 2026-09-30: 74
- 2026-09-29: 73
- 2026-09-28: 73

## Common questions

### What is the Prognyx oncology intelligence MCP server?

Prognyx oncology intelligence is an MCP server listed in the public MCP registry as com.prognyx/oncology-intelligence. Live ClinicalTrials.gov oncology trial comparison around an asset, plus landscapes and CI briefings. This page covers its hosted endpoint (https://www.prognyx.com/api/mcp).

### Is the Prognyx oncology intelligence MCP server safe to use?

Prognyx oncology intelligence scores 77 out of 100 on VerifyMCP. That is a record of what we were able to check automatically, not an endorsement. The category breakdown on this page shows every signal behind the number, including the ones we could not confirm.

### What tools does the Prognyx oncology intelligence MCP server expose?

Prognyx oncology intelligence exposes 3 tools: compare_trials, search_registry, search_briefings. Their descriptions and schemas cost roughly 339 tokens of context every time the server is loaded.

### Does the Prognyx oncology intelligence MCP server require authentication?

No. We connected to Prognyx oncology intelligence without credentials and it answered, so anything it exposes is reachable by anyone who knows the address.

### Is the Prognyx oncology intelligence MCP server still maintained?

Prognyx oncology intelligence is still listed as active in the MCP registry. We last reached this channel on 7 October 2026. Those dates come from our own scans of the registry and the channel itself, not from anything the publisher announced.

## Links

- Remote endpoint: https://www.prognyx.com/api/mcp
- Website: https://www.prognyx.com/mcp
- Changelog RSS feed: https://verifymcp.io/servers/com-prognyx-oncology-intelligence/api-mcp.xml
- Changelog JSON feed: https://verifymcp.io/servers/com-prognyx-oncology-intelligence/api-mcp.json
- HTML version of this page: https://verifymcp.io/servers/com-prognyx-oncology-intelligence/api-mcp
